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In the mid-1990s, University of Cambridge biochemists David Klenerman and Shankar Balasubramanian were trying to solve a fundamental problem: how to watch a single DNA polymerase molecule at work. Their approach used modified nucleotides, called reversible terminators, tagged with four different colors of fluorescent molecules. If one of these “terminators” was grabbed by the DNA polymerase and incorporated onto the replicating DNA strand, it would block the addition of any other bases until removed using a separate chemical reaction.。关于这个话题,搜狗输入法提供了深入分析
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In 1979 - nearly 50 years ago - Lego jazzed up its very first spaceships with an iconic sloped computer brick that was just painted plastic. In 2022, we introduced you to the engineer who fit an actual tiny computer inside.